Practice HL: Structural Modifications and Drug Action - 13.3.3 | Chapter 13: Option D – Medicinal Chemistry | IB 12 Chemistry
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HL: Structural Modifications and Drug Action

13.3.3 - HL: Structural Modifications and Drug Action

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Practice Questions

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Question 1 Easy

What structural modification is made to morphine to create codeine?

💡 Hint: Think about how adding small groups might change the properties.

Question 2 Easy

Which drug acts more quickly and is more addictive, morphine or heroin?

💡 Hint: Consider the lipophilicity of each drug.

4 more questions available

Interactive Quizzes

Quick quizzes to reinforce your learning

Question 1

What structural change is made to morphine to create codeine?

A) Methoxylation
B) Methylation
C) Esterification

💡 Hint: Focus on how small changes can affect potency.

Question 2

Which drug crosses the blood-brain barrier more rapidly?

A) Morphine
B) Codeine
C) Heroin

💡 Hint: Think about the concept of lipophilicity in drug design.

2 more questions available

Challenge Problems

Push your limits with advanced challenges

Challenge 1 Hard

Compare and contrast the mechanisms of action of morphine, codeine, and heroin, focusing on their structural differences.

💡 Hint: Focus on how each drug’s structure affects its potency and speed of action.

Challenge 2 Hard

Propose a structural modification to heroin aimed at reducing its addictive potential without eliminating its analgesic properties.

💡 Hint: Consider how structural changes influence the drug's interaction with the central nervous system.

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