Practice Lead Optimization - 13.1.3 | Chapter 13: Option D – Medicinal Chemistry | IB Grade 12-Chemistry
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Practice Questions

Test your understanding with targeted questions related to the topic.

Question 1

Easy

Define what a lead compound is.

💡 Hint: Think about its role in the drug discovery process.

Question 2

Easy

What does SAR stand for?

💡 Hint: Consider what this acronym represents in drug development.

Practice 4 more questions and get performance evaluation

Interactive Quizzes

Engage in quick quizzes to reinforce what you've learned and check your comprehension.

Question 1

What does optimizing a lead compound generally aim to improve?

  • Efficacy and safety
  • Cost and time
  • Availability and accessibility

💡 Hint: Consider the main goals of drug development.

Question 2

True or False: Potency refers to the amount of drug needed to achieve a specific effect.

  • True
  • False

💡 Hint: Think about what potency indicates in the context of drug action.

Solve and get performance evaluation

Challenge Problems

Push your limits with challenges.

Question 1

Given a lead compound with high potency but poor solubility, propose modifications that could enhance its pharmacokinetics while maintaining its therapeutic effect.

💡 Hint: Think about functional groups that are known for enhancing solubility.

Question 2

You have a drug that is effective but causes significant side effects due to off-target interactions. What strategies can you employ to increase selectivity?

💡 Hint: Reflect on how receptor specificity can be altered.

Challenge and get performance evaluation