Practice - Supercoiling (Compaction in Circular DNA)
Practice Questions
Test your understanding with targeted questions
What is supercoiling?
💡 Hint: Think about how a twisted rubber band can change shape.
What is the role of topoisomerases?
💡 Hint: Recall how they help reduce tension in DNA.
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Interactive Quizzes
Quick quizzes to reinforce your learning
What is the primary function of negative supercoiling?
💡 Hint: Think about how unwinding affects access to DNA.
True or False: Positive supercoiling helps to easily access the DNA strands.
💡 Hint: Consider the implications of winding tightly.
1 more question available
Challenge Problems
Push your limits with advanced challenges
Consider a situation where a bacterial culture is treated with a topoisomerase inhibitor. Describe the expected outcomes on DNA replication and the specific cellular consequences that may arise.
💡 Hint: Think about how unresolved tension affects biological processes.
Design a study experiment to test the effect of varying levels of supercoiling on gene expression in a prokaryotic system. What methods would you use, and what would you measure?
💡 Hint: Consider how supercoiling impacts access to promoters.
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Reference links
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