9.4.6 - Hoffmann bromamide degradation reaction
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Practice Questions
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Define the Hoffmann bromamide degradation reaction.
💡 Hint: Focus on what happens to the amide and the product.
Describe the key steps in the Hoffmann reaction mechanism.
💡 Hint: Think about the role of bromine.
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Interactive Quizzes
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What does the Hoffmann bromamide degradation reaction produce?
💡 Hint: Think about the definition of primary amines.
The rearrangement in Hoffmann reaction results in what?
💡 Hint: Reflect on the structural changes made in the process.
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Challenge Problems
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Propose a synthetic route using Hoffmann bromamide degradation to form hexanamine from hexanamide. Explain the reaction mechanism.
💡 Hint: Solve this by breaking down the reaction stages in detail.
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