Environmental Quality Monitoring & Analysis, - Vol 2 | 13. Analysis Methods – Gas Chromatography (Mass Spectrometry) by Abraham | Learn Smarter
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13. Analysis Methods – Gas Chromatography (Mass Spectrometry)

Mass spectrometry is a vital analytical method that allows for the precise examination of organic compounds through ionization and fragmentation. The methodology includes the use of a mass analyzer to separate ions based on their mass-to-charge ratio, enabling a detailed analysis of the components in a sample. This chapter discusses key aspects of gas chromatography coupled with mass spectrometry (GC-MS), including the functionality of mass analyzers, data processing for compound identification, and quantification techniques.

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Sections

  • 1

    Environmental Quality

    This section discusses the principles of gas chromatography and mass spectrometry, focusing on the functionality, components, and analytical capabilities of mass spectrometers in environmental quality analysis.

  • 1.1

    Monitoring And Analysis

    This section covers gas chromatography and mass spectrometry, focusing on the principles of mass spectrometry in analyzing organic compounds.

  • 1.2

    Analysis Methods – Gas Chromatography (Mass Spectrometry)

    This section discusses the principles and applications of gas chromatography combined with mass spectrometry for organic analysis.

  • 1.3

    Mass Spectrometer Detector And Theory

    This section explores the workings of mass spectrometers, detailing their role in organic analysis, including ionization, fragmentation, and detection of compounds.

  • 1.4

    Mass Analyzer And Detectors

    This section discusses the functioning of mass spectrometers in organic analysis, emphasizing the role of the mass analyzer and its detection capabilities.

  • 1.5

    Fragmentation And Analysis

    This section explores gas chromatography combined with mass spectrometry (GC-MS) for the analysis of organic compounds, focusing on ionization, fragmentation, and identification of various components.

  • 1.6

    Identification Of Compounds Via Mass Spectrometry

    This section outlines the principles of mass spectrometry as a technique for identifying organic compounds through ionization and fragmentation.

  • 1.7

    Library Of Standard Mass Spectra

    This section discusses the function and significance of mass spectrometry in organic analysis, particularly relating to the identification and quantification of chemical compounds.

  • 1.8

    Similarity Search In Mass Spectrometry

    This section provides an overview of how mass spectrometry analyzes organic molecules through fragmentation and how similarity searches are used to identify compounds based on mass spectra.

  • 1.9

    Quantification In Chromatography And Mass Spectrometry

    This section explores the principles of quantification in chromatography and mass spectrometry, detailing the processes involved in analyzing compounds through their mass and charge characteristics.

  • 2

    Detailed Example Of Mass Spectrum Analysis

    This section explains the principles of mass spectrometry, focusing on how mass analyzers and detectors function in analyzing organic compounds.

  • 2.1

    Mass Spectrum Peak Analysis

    This section discusses the operation and significance of mass spectrometry in organic analysis, particularly focusing on how mass spectrum peak analysis is conducted using mass analyzers.

  • 2.2

    Chemical Identification Via Reference Standards

    This section discusses the use of mass spectrometry in conjunction with gas chromatography for chemical identification.

  • 2.3

    Software And Automation In Mass Spectrum Analysis

    This section discusses the intricate workings of mass spectrometry in organic analysis, detailing its components and processes.

References

26a.pdf

Class Notes

Memorization

What we have learnt

  • Mass spectrometry involves ...
  • A mass analyzer, such as a ...
  • Comparison with library spe...

Final Test

Revision Tests