The chapter explores the significance of work, livelihood, careers, and entrepreneurship, highlighting how individuals relate their skills and passions to meaningful work. It emphasizes the cultural and economic implications of traditional occupations, the effects of gender and age on work dynamics, and the importance of a supportive work environment for personal and societal growth. Additionally, the chapter discusses the role of life skills and ergonomics in enhancing work quality and the importance of entrepreneurship in contributing to societal development.